Dostinex General Information
Dostinex is used to treat high levels of prolactin hormone in your body. High levels of prolactin in women can cause symptoms such as unwanted breast milk and missed periods and can cause difficulty becoming pregnant. High levels of prolactin in men can cause symptoms such as enlarged breasts and decreased sexual ability/desire. Dostinex is an ergot medication and works by blocking the release of prolactin from the pituitary gland.
How to Use Dostinex
Take Dostinex by mouth with or without food, usually twice a week or as directed by your doctor.
The dosage is based on your medical condition and response to treatment (prolactin levels). Your doctor will start you at a low dose and slowly increase your dose over several months to help decrease side effects. Follow your doctor's instructions carefully.
Take Dostinex regularly to get the most benefit from it. To help you remember, mark the days on the calendar when you need to take the medication.
Tell your doctor if your condition persists or worsens.
Dostinex Possible Side Effects
Nausea, vomiting, stomach upset, constipation, dizziness, lightheadedness, or tiredness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed Dostinex because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Dostinex do not have serious side effects.
Tell your doctor immediately if any of these rare but serious side effects occur: shortness of breath, persistent cough, swelling ankles/feet, unusual tiredness, mental/mood changes (such as nervousness), unusual strong urges (such as increased gambling, increased sexual urges), vision changes, painful menses, breast pain.
Get medical help right away if you have any serious side effects, including: chest pain, lower back/flank pain, change in the amount of urine.
A very serious allergic reaction to Dostinex is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
Before taking Dostinex, tell your doctor or pharmacist if you are allergic to it; or to other ergot medications (such as ergotamine); or if you have any other allergies. Dostinex may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using Dostinex, tell your doctor or pharmacist your medical history, especially of: liver disease, high blood pressure (hypertension), heart valve disease, abnormal scarring/thickening of the lining in the lungs/heart/behind the abdomen (pulmonary/pericardial/retroperitoneal fibrosis).
Dostinex may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
During pregnancy, Dostinex should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if Dostinex passes into breast milk. However, Dostinex may affect breast milk production. Therefore, breast-feeding while using Dostinex is not recommended. Consult your doctor before breast-feeding.
Dostinex Possible Intercations
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with Dostinex include: antipsychotic medications (such as chlorpromazine, haloperidol, thiothixene), metoclopramide, prochlorperazine.
Other medications can affect the removal of Dostinex from your body, which may affect how Dostinex works. Examples include certain azole antifungals (such as itraconazole, ketoconazole, posaconazole), cobicistat, macrolide antibiotics (such as clarithromycin, erythromycin), HIV protease inhibitors (such as ritonavir, saquinavir), among others.
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