The study found that the participants experienced 52 percent fewer tics on average and a 26 to 33 percent improvement in the symptoms of OCD, depression and anxiety two years after deep brain stimulation began. Deep brain stimulation had no significant effect on thinking abilities in the study.
"Despite having only 15 patients in this study, it is the largest to date on the effectiveness of deep brain stimulation as a treatment for Tourette syndrome," said Cavanna. "The results showed that all 15 people who were assessed after two years' treatment experienced improvements in disabling tics and neurological problems, which is encouraging. Unfortunately three patients from the original group of 18 were no longer part of the study at follow up and this limits the ability to generalize our findings. More research needs to be done to confirm that deep brain stimulation is a safe and effective treatment for Tourette syndrome."
Deep brain stimulation is FDA approved for the treatment of essential tremor, Parkinson's disease and dystonia.
Source: The American Academy of Neurology